Department of Biochemistry

COURSE OUTLINE

100 Level

First Semester

Second Semester

200 Level

First Semester

Second Semester

300 Level

First Semester

Second Semester

*All 300Level Students are expected to proceed to the mandatory six (6) months industrial training scheme in the second semester in any established industry/firm where they would gain more laboratory experience.

400 Level

First Semester

Second Semester

*Electives: Elective courses may be taken in addition to core and Required courses. Maximum credit load per semester is 24 units. 

DESCRIPTION OF COURSES

BCH 211: INTRODUCTORY BIOCHEMISTRY I (3 CREDITS)

Short history and definition of biochemistry. Importance of Biochemistry to other scientific disciplines. General considerations on the biological molecules of life (carbohydrates and lipid) ---- Introduction-Definition, functions, classification, Types- monosaccharides, disaccharides, oligosaccharides & polysaccharides, Isomers (Stereo & optical isomerism, epimers, anomers, mutarotation, enantiomers), Reducing properties (oxidation & reduction), dehydration, osazone formation, ester formation, Glycosides. Classification of lipids- fatty acids, triglycerides, glycosylglycerols, phospholipids, waxes, prostaglandins. lipid micelles and bilayers, Monolayers and Bilayers Lipoprotein system. General properties of enzymes as biological catalysts. pH and pKa values and their effects on cellular activities. pH scale, measurement of pH, acids and bases, acid-base indicator.  Titration curves of acids and bases. Buffer and buffer Systems.  Energy generation and storage in biological systems.

BCH 212: EXPERIMENTAL BIOCHEMISTRY I (2 CREDITS)

This is an introductory laboratory course for students in Biochemistry and Microbiology. The experiments include: Qualitative analysis of some important biochemical substances such as proteins, amino acids, carbohydrates, lipids, nucleic acids, enzymes etc; estimation of glucose by iodine oxidation in alkaline conditions, determination of ascorbic acid using 2, 5 dichlorophenol indophenols and estimation of amino acids by formal titration.

Text: Departmental laboratory practical manual.

BCH 220: INTRODUCTORY BIOCHEMISTRY II (3 CREDITS). Amino acids as building blocks of proteins, amino acid sequence of proteins, covalent backbone of proteins. Chemistry/structure/Reactions/classification of amino acids, Properties of the peptide bond. Levels of organisation of proteins. Protein isolation, fractionation, purification and characterization. Biological functions of proteins. Genome organization. Evidence for DNA as the carrier of genetic information. Purines and pyrimidines, Nucleoside and Nucleotide Structure and Nomenclature, abnormalities in nucleic acid metabolism, Structure of RNA & DNA.DNA Organization into Chromosomes. Early foundation for DNA structures, Forces involved in DNA helices, Denaturing and Annealing, Hypochromic Effect, Erwin Chargaff`s rule. Metabolism of one carbon units, metabolism of inorganic nitrogen.

BCH 221: METABOLISM OF CARBOHYDRATES AND LIPIDS (3 CREDITS).

Degradation and digestion of carbohydrate-(sugars), storage polysaccharides and cell walls. Introduction to metabolism. Metabolism of lipids; fatty acids and triglyceride degradation; lipoproteins; membranes and membrane structure (elementary introduction). Metabolism of carbohydrates: glycolysis, TCA cycle, pentose phosphate pathway.Cori cycle, Calvin pathway, glycogenesis/Glycogenolysis, glyoxylate cycle, gluconeogenesis. Entry of fructose, galactose and other hexoses into the glycolytic pathway. Uronic acid pathway with its biomedical importance. Regulation of blood sugar & biochemical basis of complications of diabetes, Metabolism of carbohydrates in fed & fasting state. Disorders of carbohydrate metabolism. Electron transport and oxidative phosphorylation. Accessory food factors and trace elements: their importance in nutrition and role in metabolism. Convergence of metabolic pathways.

 BCH 222: FUNCTIONAL BIOCHEMISTRY (2 CREDITS)

An introduction to biochemical information flow, strategies of signalling (physical and chemical) presented in a hierarchical fashion. Hormones and neurotransmitters as chemical mediators of signals in plant and animals. An outline of the physiological action of auxins, gibberellins, cytokinins, insulin, Parathyroid hormone, estrogens and androgens. Ligand-gated nerve of nerve impulse (action potential, acetylcholine and other neurotransmitters e.g. GABA serotonin, norepinephrine). Signal transduction cascades to highlight the roles of cAMP, IP₃. diacylglycerol and Ca²⁺ ions in sensing and processing stimuli. Composition of muscle and biochemistry of muscle contraction.

BCH 223: BIOENERGETICS (2 CREDITS)

Reaction orders, first, second, third and zero order reactions. High-energy compounds; chemical potentials, electrochemical potentials, electron transport system and oxidative phosphorylation. Regulation of ATP production. Biological oxidation-reduction reactions. Catalysis and activation energy. Buffers and buffer systems. Chemical  Transport across biological membranes.

BCH 224:  BASIC IMMUNOLOGY (3 CREDITS).

Basic immunology.Fundamental concepts of immunity, humoral and cellular products of immunity, cells of the immune system.Natural and acquired immunity. Antigens: Structure and classification. Antibodies: Structure and function. Structure-function relationships. Synthesis of antibodies, organization/structure/characteristics of immunoglobulin and molecular basis of antibody diversity Antibody diversity.Antigen-antibody reactions. Production, detection and uses of monoclonal antibodies.The complement system. Major Histocompatibility Proteins, Mononuclear phagocytic cells, Granulocyte cell population, Agglutination reactions, Hypersensitivity and allergies. Therapeutic and prophylactic applications of immunology. Immune tolerance, autoimmunity, transplantation immunity, immunology of reproduction.Cancer biology and immunology. Radioimmunoassay, Immunoelectrophoresis.

BCH 310: INTRODUCTORY MOLECULAR BIOLOGY (2 CREDITS)

Cellular ultra structure: chromosome structure and gene expression. A more comprehensive study of the pathway of biological information transfer processes comprising detailed analysis of replication, transcription and translation. Central dogma of molecular biology, DNA and RNA polymerase in prokaryotes and eukaryotes. Histones and molecular chaperones, prokaryotic gene expression and control (lac operon, trp operon), Eukaryotic gene expression and control. DNA damage and repair, DNA damaging agents, types of damage of DNA, pathological manifestations of defective DNA repair including Xerodermapigmentosum, Ataxia telangiotasia, Fanconi`s anaemia and Cockayne syndrome

BCH 311: EXPERIMENTAL BIOCHEMISTRY II (2 CREDITS).

The topics covered in this laboratory course include hydrogen ion concentration with emphasis on buffers and the ionisable groups of amino acids, working with carbohydrate (quantitative determination of glucose and other reducing sugars using somogyi Nelson method, glucose oxidase method, O`toluidine method; methods of cell fractionation, enzyme purification and kinetic characterisation of an enzyme, methods of separation of proteins using chromatography techniques, centrifugation, methods of protein quantification; spectrophotometry; experimental approach to the study of plasma membrane proteins and glycoproteins.

BCH 312: INTRODUCTION TO ENZYMOLOGY (3 CREDITS).

Vitamins and co-enzymes.Fat and water soluble vitamins.Structures and functions of vitamins and co-enzymes. Genetics of enzymes and inhibition. History of enzymology, definition, enzyme as catalyst, general characteristics, nomenclature, nature of enzymes.Genetics of enzymes and inhibition. Levels of structural organization; active site, nature of active site, enzyme kinetics, analytical enzymes – isolation, purification and characterisation of enzymes and measurement of enzyme activity – methods and principles. Analytical enzymes. Mechanisms of enzyme catalyzed reactions. Effects of temperature, pH, ions and inhibitors on enzyme catalysed reactions. Michaelis-Menton equation allosteric/regulatory enzymes. Estimation of kinetic parameters- enzyme activities, Km, Vmax, Ki etc.Zymogen activation, digestive enzymes etc. Recent advances in enzymology.

BCH 313: TECHNIQUES IN BIOCHEMICAL RESEARCH  (2 CREDITS).

Separation techniques in biochemistry.The principles, procedures, and application of centrifugation, chromatography, electrophoresis and analytical techniques.  The principles, instrumentation, and application of the following: Manometry, Photometry (Spectrophotometry, Spectrofluorimetry and flame photometry), Calorimetry, optical spectroscopy, X-ray diffraction. Mass and Nuclear Magnetic Resonance, Spectrometry.  Radioimmunoassay, pH measurement, Isotopes in Biochemistry

BCH 314: AMINO ACID, PROTEIN AND NUCLEIC ACID METABOLISM (2CREDITS)

Detailed treatment of metabolism of amino acids degradation and biosynthesis.Inborn errors of metabolism. the urea cycle; metabolism of inorganic nitrogen. Disorders of amino acid metabolism. Oxidative and Non-oxidative deamination, Transamination and decarboxylation, Transamidation, Transport and toxicity of ammonia, Creatine metabolism. Polyamines. Nucleoside, nucleotide and nucleic acid synthesis/degradation. Disorders of nucleotide metabolism. Hyperuricemia & other inborn errors. One carbon metabolism, Transmethylation. Protoporphyrin synthesis in animals and plants. Hormone and regulatory role in intermediary metabolism.

BCH 315: FOOD/NUTRITIONAL BIOCHEMISTRY (3 CREDITS).

Human dietary nutrient requirement and factors affecting the requirements. Food habits and intakes. Digestion, absorption, metabolism and function of carbohydrates, lipid, proteins and  amino acids in mass.  Consequences of excess and inadequate calorie intake, protein energy malnutrition.Kwashiokor and Marasmus. The vitamins: Their chemistry, metabolism and function, The minerals: Their metabolism and function. Animal and microbial nutrition.  Feed formulation, food toxicants and detoxification mechanisms. Food stuff: Nutritive and energy values and protein quality. Nutritional disorders, prevention and therapy. Nutritional status and nutritional requirements.Assessment of nutritional status.

Public health aspects of nutrition; nutrient requirement in relation to physical activity and ageing, diet and disease, obesity and under nutrition.Assessment of nutritional status; aetiology of malnutrition. Environmental and social factors related to malnutrition.

BCH 316: BIOMEMBRANES (3 CREDITS).

The central dogma of membrane biology (the fluid mosaic model), Membrane functions, types and composition: Lipid structure, properties and formation of the  bilayer; protein and carbohydrates. Membrane structure and integrity.Membrane asymmetry and movements, diffusion, rotation and fluidity. Isolation and identification electron microscopy and marker enzyme assays. Introduction to receptor function: antigenicity of membrane components. Cell membrane and toxins, transport processes, action of polymyxin and ionophores.Introduction to neurotransmission. Membrane transport system- active versus passive transport systems. Transport of sugars and amino acids.Defence mechanism in parasites.  Biomembranes of parasites.

BCH 317: BIOCHEMISTRY OF HORMONES (2 CREDITS).

Biochemical aspects of endocrinology, hormones, structures and functions. Evolution of hormone action, classes of hormones, intercellular mediators of hormones, hormone receptors, binding activity and response. Molecular mechanisms of action of steroids, thyroid and polypeptide hormones.Kinetics of binding mode of action of hormones, cAMP as second messenger, role of calcium and other ions.  Amino acid derived hormones, steroid hormones and polypeptide hormones.  Hormone agonists and partial agonists.Biochemistry and function of insulin, glucagon and other hormones controlling carbohydrate metabolism. Endocrine and regulatory systems mediated by cyclic AMP.  Chemistry and functions of hormones:  Storage and secretion:  steroid hormones; Parathyroid hormones.  1, 2, 5-Dihydroxy-cholecalciferol and calcitonin. Prostaglandins.

BCH 328: STUDENTS INDUSTRIAL TRAINING SCHEME FOR   6 MONTHS – (6 CREDITS).

Students will be attached to biochemistry training research institutes/organization/body for 6 months. The organization so attached must bear relevance to the students area of specialty emphasizing biochemical knowledge and scientific principles.

Lecturers shall be assigned to visit the students at least once.

At the end of the industrial attachment, Students are expected to submit a written report ( three copies in hard bound cover) and present a departmental seminar on their Industrial Training experience.

BCH 411: ADVANCED ENZYMOLOGY (2 CREDITS).

Enzyme structure and properties. Steady state enzyme kinetics. Transient kinetic methods. Chemistry of enzyme catalysis. Regulatory enzymes. Molecular models for allosterism. Enzyme assemblages, principles of catalysis, multienzyme systems, allosterism and enzyme inhibition. Regulation of enzyme activity and synthesis; chemical modification of enzyme activity, enzyme reaction mechanism. Enzyme assays. Criteria to determine enzyme purity. Enzyme reconstitution

BCH 412: ADVANCED INTERMEDIARY METABOLISM AND REGULATION (3 CREDITS).

Advanced studies in degradation and synthesis of biological compounds.Carbohydrate degradation and synthesis, and regulatory processes.Lipid, protein, purines and pyrimidine degradation and synthesis and regulatory process. Endocrine system and mechanism of hormone control of metabolism. The relationship of Citric acid cycle to protein, carbohydrate, lipid and nucleic acids.Integration of metabolic pathways.Turn-over rates and metabolic pools.Regulation of enzymes of metabolic pathways-feed back inhibition versus enzyme synthesis.Catabolite repression, end product repression.Identification of different regulatory mechanism in metabolic pathways.

BCH 413:  ADVANCED MOLECULAR BIOLOGY (3 CREDITS)

Recombinant DNA and gene cloning.Extra-chromosomal factors, plasmids, episomes.Genetic control of viral replication, Model systems used for studying embryology (differentiation) at the molecular level. Model systems in differentiation studies. Control of cell proliferation, molecular genetics of the haemoglobinopathies. Poymerase chain reaction: Application in biotechnology. Vector biology. SDS-PAGE, Southern, Northern and Western blotting. Genomic libraries, construction and screening. Genomics and metagenomics. Introduction to microarray. Restriction enzymes, DNA Library, Gene Mapping, Restriction Fragment Length Polymorphism, Gene Knockout, Gene Therapy, Human Genome Project. Etiology of cancer, Biochemical changes in cancer cells, Role of oncogenes, proto-oncogenes & tumor suppressor genes, Action of Growth Factors on cell cycle and mitosis, Cancer Chemotherapy, Biochemical basis of metastsis, Evaluation of Tumor Markers in cancer management. Biochemistry of Stem cell/tissue regeneration

BCH 414: BIOCHEMISTRY OF ORGANS AND TISSUES (3 CREDITS).

Intracellular organization, structure and functions of specialized tissues – liver, kidney, pancreas, testes, spleen, muscles, adipose tissue, elastin, collagen, brain, ear. Functional aspects of neural biochemistry:  membrane potential and transport.  Neurotransmitters and biogenic amines in the brain.Constitution and function of blood, lymph and other fluids. Biochemistry of the eye and vision.

BCH 415: CLINICAL BIOCHEMISTRY AND PHARMACOLOGY (3 CREDITS).

The course covers the theoretical basis of laboratory tests of clinical significance in diagnosis and management of diseases. Routine tests of general wellbeing- urine, blood, renal function tests and electrolyte balance; liver function test. Endocrine function assessment; immunochemistry Introduction to pharmacological concepts, Drug administration, absorption, distribution and receptors. Xenobiochemistry, Drug metabolism, Drug metabolizing enzymes and drug interactions. Role of Cytochrome P450, Various mechanisms of Detoxification.

Biochemical basis of drug resistance. Drug design. Theories of the mechanism of drug action. Drug resistances and other factors affecting drug efficacy. The physiological and biochemical action of some selected drugs. Reactive oxygen species - mediated toxicity. Nigerian traditional medicinal plants in the management and therapy of common ailments in Nigeria- malaria, sickle cell anaemia, common cold, hepatitis etc. Comparison of the metabolism of biomolecules. Biochemical mechanisms of drug action against parasites.  Metabolic factors affecting chemotherapeutic agents.

BCH 416: FORENSIC BIOCHEMISTRY (2 CREDITS)

Extraction and purification methods of antibiotics. Clinical uses of antibiotics. Procedure for the extraction of contaminants of forensic from tissues. Collection and preservation techniques for materials of forensic interest. Analytical procedures in forensic medicine. Law, science and medicine in forensic practices          

BCH 417: SEMINARS AND BIOCHEMICAL LITERATURE (2 CREDITS)

Courses to cover reading assignments to students which are expected to be completed during 3-6 hours library studies and later presented as short seminars. One lecture weekly on growth and development of Biochemistry emphasizing major breakthrough in Biochemical research.

BCH 418: BIOINFORMATICS (2 CREDITS).

This is a survey course which provides an overview of current applications of computational techniques in life science laboratories. It discusses the most important strategies and resources for annotation of biological sequences on the internet, their judicious application and the interpretation of results. Lectures will normally be introduces through the pre-reading material. Assignments will complement the lectures by practicing techniques of computational molecular data analysis, with an emphasis on web based tools.

BCH 419: BIOCHEMISTRY AND IMMUNOLOGY OF PARASITIC DISEASES (2 CREDITS)

Types of parasitic protozoa: methods of control of parasitic diseases, Techniques for the isolation of parasitic protozoa from infected animals. Culture of parasitic protozoa. Catabolism and generation of energy: nucleic acid metabolism, Protein metabolism and lipid metabolism. Biochemical mechanism of drug action. The immunology and plasma membrane of parasitic protozoa

BCH 420: BIOCHEMICAL REASONING (2 CREDITS).

Evaluation and design of experimental biochemistry from available information and data. Analysis, interpretation and inference- drawing from biochemical research data. Problems solving in biochemistry using examples from the literature. This should consists of take home assignments to be discussed later in class.

BCH 421: ADVANCED FOOD/NUTRITIONAL BIOCHEMISTRY (3 CREDITS)

Biochemical changes in food, meat, fish, fruits.  Enzymatic browning and bio-deterioration of food products: vegetable and oils, milk and milk products, cereal formula. Food processing; Food additives and preservatives. Food processing, preservation and storage of traditional foods- root and stem tubers, fruits and fruit drinks, seeds and grains, green vegetables. Food nutrients. Energy values of food and energy expenditures by mammalians. Quality control of food. Continuous culture methods, principle and application. Fermentation—alcoholic, amino acids, antibiotics and other secondary metabolites. Fermentation Biotechnology---Beer, wine and spirit production. Process evaluation and development. Over production of metabolites - amino acids, taste enhancers, vitamms, toxin etc. Methods for screenmg and selecting micro-organisms of industrial importance. Induction of mutation in micro-organism and plants for the purpose of over production; Strain selection/development and enhancement. Gene dosage and its application in industrial processes.

BCH 422:  PROJECT(6 CREDITS)

Literature survey and planned laboratory work to be written up as a project under the supervision of a member of staff.

BCH 423: BIOTECHNOLOGY (3 CREDITS)

Biochemistry of microbial growth: energetics and kinetics of microbial growth. A review of general metabolic pathways and application in industrial processes. Continuous culture methods, principles and applications. Downstream processing in biotechnology and general instrumentation. Fermentation- alcoholic, amino acid antibiotics and other secondary metabolites. Primary and secondary metabolism. Process evaluation and development.The chemostat and its application in industrial fermentations. Microbial gums and other polymers. Over-production of metabolites- amino acids, taste enhancers, vitamins, toxins etc. Methods for screening and selecting micro-organisms of industrial importance. Strain selection/development and enhancement. Enzyme production: immobilized enzymes and applications.  Pollution control, genetic engineering; Application in biotechnology. Gene dosage and its application in industrial processes

BCH 424: PLANT BIOCHEMISTRY (3 CREDITS).

General description of sub-cellular components of plant cell and methods of fractionation.  Structure/formation/growth of primary cell wall.  Organization of plant cells, Complex carbohydrates of plants. Chemistry and metabolism. Aspects of nitrogen metabolism in plants. Mineral metabolism. Plant hormones. Biosynthesis of carotenoid pigments. Biochemistry of plant development. Lignin formation. Free amino acids, pyrimidines, purines and nucleosides in plants. Metabolism of auxins, gibberellins and cytokinins. Synthetic growth regulators and herbicides. Structure/function relationship of plant hormones. Biochemistry of plant development including seed development and germination. Autotrophy (photosynthesis).Phytochemistry

BCH 425: ADVANCED IMMUNOLOGY (2 CREDITS).

This course covers the fundamentals of clinical immunology and mechanisms of immunopathology. Tissue reactions of injury, allergic disease and cancer immunology. Immunological Disorders, Immunotherapy, Immunomodulators and Immuno  suppressive Immunoglobulin Replacement Therapy. Cytokine and Cytokine Receptor-Mediated Therapy Cellular Immune Reconstitution, Immunoprophylaxis Vaccine. Parasite Escape within Hosts, Natural Selection of Antigenic, Variants, Pathogen Manipulation of Host, Immune Dynamics, Sequence of Variants in Active, Switching from Archives. Polymorphisms in Immune Regulation

BCH 426: BIOCHEMICAL ENGINEERING (2 CREDITS).

Introduction- Definations (Dimemensions and Units).Scope of biochemical engineering. Microbial Growth –Requirements for growth, types of media, the batch culture, mathematical model of simple batch culture, diaxic growth. Factors affecting growth and product formation.Unit Operations –Material and Energy balance. Heat transfer coefficient. Application of heat transfer (sterilization, canning, pasteurization, chilling and freezing, refrigeration. Food processing.

BCH 427: ENVIRONMENTAL BIOCHEMISTRY AND TOXICOLOGY (2 CREDITS).

Fundamentals of ecotoxicology; environmental impact assessment; biomonitoring. Classification of toxicology, Bioassays, Poisons :definitions and mechanisms of action. Molecular and cellular mechanisms of toxicity and carcinogenesis.

 NON-GENERAL COURSES FROM OUTSIDE THE DEPARTMENT

AEB 111: Introduction to Animal and Environmental Biology (3 units) 2+0+1

Macromolecular basis of life: cellular basis of biological organization; cell structure and function; the organism and its environment. Man, population, growth, Environmental Pollution and impact on the biosphere; Fauna biodiversity: Invertebrata (Protozoa, Porifera, Coelenterata, Platyhelminthes, Nematoda, Annelida, Arthropoda, Mollusca, Echinodermata. Vertebrata (Cephalochordata, Amphibia, Pisces, Reptilia, Aves, Mammalia.

AEB 122: Vertebrate Zoology (3 units) 2+0+1

Identification, phylogeny, biology and economic importance of: Cephalochordata, Hemichordata, Urochordata, Agnatha, Pisces, Amphibia, Reptilia, Aves and Mammalia of Nigeria. Students are expected to dissect the fish.

PBB 111: Introduction to Plant Biology and Biotechnology (3 units) 2+0+1

Introduction to plant biology and biotechnology; career prospects and areas of specialization; brief history and applications of biotechnology; cells and molecules in plants; diversity of living organisms and habits, life forms, mode of nutrition, size and shape; classification of living organisms; concept of five kingdom, their characteristics and possible evolutionary relationships among groups of organisms.

PBB 122 – INTRODUCTION TO PLANT FORM AND FUNCTIONS (3 CREDITS)

2 Lecture Hours and 2 Practical Hours per week

Plants – structures and functions; Plants and their adaptations to environment

The general morphology of flowering plants.

Plant tissues and growth hormones.

Anatomy of flowering plants- origin and development of primary and secondary plant body.

Physiology of flowering plants.

Plant metabolic pathways.

Practical:

All items included in theory.

CHM 111: Introductory Chemistry I         (3 unit)

Atomic theory and Nature of atoms. Introduction to the periodic table: properties and Electronic configuration. Stoichiometry: formulae and Equations, Volumetric analysis, redox precipitation and complexation reactions.  States of matter: Gases, Liquids and solids. Gas laws. General gas equations. Electrochemistry and Redox reactions. Chemical Kinetics, rate orders and rate laws.  Chemical equilibrium, Nuclear Chemistry and Radioactivity.

CHM 112: Introductory Chemistry Practical I (1 unit)

A selection of experimental exercises, designed to illustrate principles discussed in CHM 111 lectures which includes: making measurement, identification of cations and anions, preparation of standard solutions, stoichiometry, volumetric analysis, redox titration.

CHM 123:  Introductory Chemistry II      (3Unit)

Identification of organic compounds: General procedure for isolation and purification of organic compounds, Elemental (Qualitative) analysis. Quantitative analysis. Shapes of organic molecules: Lewis structure, Valence shell electron pair repulsion (VSEPR) theory and Hybridization. Stereochemistry, Chemistry of hydrocarbons (alkanes, alkenes and alkynes, alkyl halides and Grignard reagents, aromatic compounds). Introduction to petroleum coal tar chemistry: Origin. Importance. Fractional distillation of crude oil. Octane rating, Cracking and reforming.  Alcohols and phenols: (syntheses, application and test).  

CHM 124: Introductory Chemistry Practical II  (1 unit)

A selection of experimental exercises, designed to illustrate principles discussed in CHM 123 lectures which includes: separation techniques (recrystallization, filtration), melting point determination, elemental analysis (Lassaignes sodium fusion test), functional group identification, synthesis of aspirin, preparation of soap.

CHM 215: Experimental Chemistry I (2 unit)

Qualitative Inorganic preparations and analyses; separation techniques; Redox titrations; Acids and Bases- Titration of monobasic acids and monobasic bases using indicators and pH meters. Buffers; determination of rate constant.

CHM 312: Advanced Organic Chemistry

Alcohols and their reactions; ethers and epoxides; reactions of aldehydes and ketones; reactions of alpha and beta unsaturated compounds; aromatic and alicyclic chemistry; polyfunctional compounds and heterocyclic chemistry, chemistry of bicyclic compounds.

CHM 314: Advanced Physical Chemistry (3 Units)

A review of Gibbs Function. Chemical thermodynamics. Introduction to statistical thermodynamics. Ideal solutions. Non-Ideal solutions. Properties of electrolytes. Colligative Properties.

CSC 111: Introduction to Computer Systems (2 Units)

History of computers, Classification and types of computers, computer application in commercial and scientific environments, characteristics of computers, Functional components of computers. Introduction to software, Input/output peripheral devices, their advantages and disadvantages, Problem solving, binary system and number components, symbolic names, array subscript, expression and control statements, data representation, number representations, Boolean algebra, data storage, file management, algorithms, and relational databases

MTH 111 GENERAL MATHEMATICS I (ALGEBRA AND TRIGONOMETRY)

Real number system. Simple definitions of integers, rational and irrational numbers. Set theory and notations: subsets, union, intersection, complements. Venn diagrams. Binary operations and its properties: closure, distributive, associative, commutative laws with examples. Real sequences and series. Elementary ratios of convergence of arithmetic, geometric and other simple series. Theory of quadratic equations. Polynomials and partial fractions. Simple inequalities. The principle of mathematical induction. Addition and factor formulae. Complex numbers. Algebra of complex numbers, the Argand diagram, De Moivre’s theorem, nth root of unity. Permutation and Combination. The Binominal theorem.

MTH 121 GENERAL MATHEMATICS II (CALCULUS)

Elementary function of single real variable and their graphs, limits and the idea of continuity. Graphs of simple functions polynomial, rational, trigonometric, etc. rate of change, tangent and normal to a curve. Differentiation as limit of rate of change of elementary functions, product, quotient, function of function rules. Implicit differentiation, differentiation of trigonometric, inverse trigonometric functions and of exponential functions. Logarithmic and parametric differentiation. Applications of differentiation: Tangent and normal to a curve. Stationary values of simple functions: maxima, minima and points of inflexion, area of surface revolution. Integration as an inverse of differentiation. Techniques of integration. Definite integrals.  Applications of integration to areas and volumes.

PHY 111      GENERAL PHYSICS I  (3 UNITS)

Measurements, Rectilinear Motion, Vector Space,  Kinematics and Dynamics, Work, Energy and Power, Conservation Laws, Momentum and Conservation of Momentum, Elastic Properties of Material, Surface Tension, Adhesion, Cohesion, Capillarity, Projectile Motion, Pressure, Newton’s Law of Gravitation, Satellite, Escape Velocity

Circular Motion, Periodic Motion, Velocity and Acceleration of a Sinusoidal Oscillation, Force Oscillation, Resonance, Propagation and Behavior of Waves, Types, Classes and Properties of Waves, Light Waves, Mirror and Lenses, Temperature, Heat, Gas Laws, Thermodynamics Laws, Kinetic Theory of Gases.

PHY 119 GENERAL PHYSICS PRACTICAL I                                       (1UNIT)

Quantitative Measurement, Measurement of Errors, Experiments and Graphical Analysis.

*Note: The students are expected to carry out minimum of five (05) practical in the area of mechanics, waves and thermal for the academic session.

 PHY121:   GENERAL PHYSICS II (3 UNITS)

Electrostatics,  Coulomb’s Law, Electric Field, Conductors, Electric Current, Ohm’s Law, Simple Circuit, Kirchhoff’s Laws, Capacitor and Capacitance. Magnetic Field and Induction, Electromagnetic Forces and Effects and Maxwell’s Laws, Atomic Structure, Models and Theory, X-Rays, Planck’s Quantum Theory, Duality of Matter, Structure and Composition of Nucleus.

ADMISSION REQUIREMENTS

U.T.M.E Requirements

Admission into preliminary courses for a degree in Biochemistry at Edo University will be the University Matriculation Examination (UME), which shall be open to candidates who have obtained credits in at least five subjects at the G.C.E. ordinary level or at the West African School Certificate Examination/Senior Secondary School Certificate Examination or equivalent at not more than two sittings.  The five subjects obtained must include English Language, Mathematics, Physics, Chemistry and Biology.

Direct Entry Requirements:

In addition to satisfying the matriculation requirements as stated for candidates seeking admission to First Year courses, candidates for direct entry into the second year courses must:

1. Have passes at the advanced level GCE or HSC in Chemistry and in at least one of the following: Biology, Physics, or Mathematics; or
2. Have OND in relevant area from a recognized polytechnic with at least a credit pass.